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加入我們創(chuàng)新的裂解酶研發(fā)團隊
我們正在尋找一位積極進取、技術(shù)精湛的博士級科學(xué)家加入我們充滿活力的團隊。我們是一家在裂解酶領(lǐng)域擁有廣泛國際影響力的領(lǐng)先公司，擁有多款一流的產(chǎn)品。
工作內(nèi)容：
您將在研發(fā)新型裂解酶的過程中發(fā)揮關(guān)鍵作用，并將其用于治療耐藥細菌。您將加入我們世界領(lǐng)先的溶菌素研發(fā)平臺，并在兩位來自美國頂尖大學(xué)的博士科學(xué)家的指導(dǎo)下開展工作。
工作職責(zé)包括領(lǐng)導(dǎo)一個研發(fā)項目，以識別和驗證針對特定目標(biāo)生物體的靶分子。以下技能對于成功的候選人至關(guān)重要：
? 分子生物學(xué)：設(shè)計和執(zhí)行涉及分子克隆的實驗，包括質(zhì)粒構(gòu)建、PCR引物設(shè)計和測序結(jié)果分析。
? 微生物學(xué)：分離和操作菌株，尤其是苛性厭氧菌，嚴格遵守?zé)o菌操作規(guī)程，并進行MIC測試、生物膜研究以及厭氧操作臺的使用等實驗。
? 實驗開發(fā)：具備高通量篩選和96/384孔板實驗經(jīng)驗。具備機器人系統(tǒng)使用經(jīng)驗者優(yōu)先！
? 蛋白質(zhì)科學(xué)：運用多種生化技術(shù)純化和表征重組蛋白。
? 數(shù)據(jù)管理：維護詳細準確的實驗數(shù)據(jù)記錄，并及時向團隊負責(zé)人提交報告。
我們尋求的人才：
? 獨立且清晰的科學(xué)思維：能夠開發(fā)、設(shè)計和開展創(chuàng)新研究。能夠理解科學(xué)論文和專利。
? 團隊合作：我們的研發(fā)團隊是一個團結(jié)協(xié)作、廣泛合作的團隊。您必須能夠有效地協(xié)作以實現(xiàn)您的目標(biāo)。
? 教育背景：該職位要求博士學(xué)位。學(xué)科方向可為微生物學(xué)、生物技術(shù)或相關(guān)領(lǐng)域。
? 經(jīng)驗：雖然擁有行業(yè)經(jīng)驗者優(yōu)先，但我們更看重擁有扎實基礎(chǔ)知識和科研熱情的候選人。我們非常重視之前與致病菌相關(guān)的工作經(jīng)驗。
? 技能：具備強大的分析和解決問題能力。能夠設(shè)計和執(zhí)行邏輯清晰、定義明確的實驗。優(yōu)秀的書面和口頭溝通能力（大學(xué)英語六級或同等水平）。您需要能夠用英語撰寫報告。
? 加分項：具備在良好實驗室規(guī)范 (GLP) 環(huán)境下工作的經(jīng)驗；動物模型（小鼠/大鼠）使用經(jīng)驗；熟悉不同的蛋白表達系統(tǒng)（例如，無細胞表達系統(tǒng)、酵母表達系統(tǒng)等）；能夠使用 Python 編程。
Join Our Innovative Endolysin Discovery Team
We’re
seeking a highly motivated and skilled PhD-level Scientist to join our dynamic
team. We are a leading company with large international footprint in the
endolysin field with several best-in-class products.
What You’ll Do:
You’llplay a crucial role in the discovery of novel endolysins for use as
therapeutics to solve the problem of drug-resistant bacteria. You will join our
world-leading endolysin discovery platform and work under the supervision of
two PhD scientists from a top-tier US university.
Responsibilities will include
leading a discovery project to identify and validate target molecules for
defined target organisms. The following techniques are important for a
successful candidate:
·
Molecular Biology: Designing and executing experiments involving molecular cloning – including plasmid construction, PCR primer design, and analysis of sequencing results.
·
Microbiology: Isolating and working with bacterial strains, especially fastidious anaerobic bacteria,
maintaining strict sterile techniques, and performing assays such as MIC
testing, biofilm studies, and utilizing an anaerobic hood.
· Assay Development: Experience with high throughput screening and 96/384-well plate assays. Experience with robotic systems is a plus!
· Protein Science: Purifying and characterizing recombinant proteins, utilizing a range of biochemical techniques.
· Data Management: Maintaining detailed and accurate records of experimental data and preparing timely reports for the team lead.
What We’re Looking For:
· Independence and clear scientific thinking: Ability to develop, design, and perform innovative research. Ability to understand scientific articles and patents.
· Team work: Our discovery team is a cohesive team that collaborates extensively. You must be able to collaborate effectively to achieve your goals.
· Education: PhD degree is an absolute requirement for this position. Subject could be in Microbiology, Biotechnology, or a related field.
· Experience: While prior industry experience is an advantage, we value candidates with strong foundational knowledge and a passion for research. We greatly value prior experience working with pathogenic bacteria.
· Skills: Strong analytical and problem-solving skills. Ability to design and execute logical and well-defined experiments. Excellent written
and verbal communication skills (CET-6 or equivalent proficiency in English).You will be expected to be able to write reports in English.
· Bonus Points: Experience working in a GLP environment; experience with animal models (mouse/rat);experience with different protein expression systems (for example, cell-free expression system, yeast expression system, etc.); ability to program in python.